• 알부민 제거율 >95% (30분 이내)
• 단백질 구조 및 활성 보존
• 다양한 분석 플랫폼과 호환
• 종 특이성 없음
• 분자량 및 pl 편향 없음
• BASP™ 기반 On-bead workflow 지원
• iTRAQ 및 label-free LC-MS 호환

Paulsen, Bruna, et al. "Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment." bioRxiv (2024): 2024-04.

The investigators performed secretome proteomics to investigate proteins overexpressed in OSC. The conditioned media was passed through albumin depletion columns (AlbuVoid) to eliminate HSA-derived albumin.

Jenull, Sabrina, et al. "The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence." Cell Reports 36.3 (2021): Link.

Cell-free supernatants were used for Mass-Spec analysis. Collected supernatants were treated with AlbuVoid™ for albumin depletion; Albumin-free enriched secretory proteome was eluted from beads.

Paulsen et al., Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization, Cell Stem Cell (2025).

AlbuVoid™ enrichment helped in characterizing key functionalities of hiPSC-derived cell lines.

Golden, Lesley R., et al. "APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition." Nature Neuroscience (2025).

ApoE enrichment with AlbuVoid™ helped in identifying the closely related ApoE4/2 variants by targeted plasma proteomic analysis.

Sae-Lee, Wisath, et al. "The protein organization of a red blood cell." Cell Reports 40.3 (2022).

The supernatant was treated with AlbuVoid to reduce the presence of serum albumin for plasma preparation.

Vialaret, Jerome, et al. "Albumin depletion of human serum to improve quantitative clinical proteomics." Current Topics in Peptide & Protein Research (2018).

AlbuVoid™ depletion method proved to be faster and more cost-effective than antibody based methods for biomarker enrichment.

Jing, Lun, et al. "PROTEOMIC ANALYSIS IDENTIFIED LBP AND CD14 AS KEY PROTEINS IN BLOOD/BIPHASIC CALCIUM PHOSPHATE MICROPARTICLE INTERACTIONS." Acta Biomaterialia (2021).

Describes use of HemoVoid™ and AlbuVoid™ prior to LC-MS analysis to identify changes in 27 signaling pathways.

Poillet-Perez, Laura, et al. "Autophagy maintains tumour growth through circulating arginine." Nature (2018).

AlbuVoid™ was used to remove albumin from mice serum and enrich low abundance proteomes to study autophagy.

Zheng H, et al. "AlbuVoid™ Coupled to On-Bead Digestion – Tackling the Challenges of Serum Proteomics." J Proteomics Bioinform (2015).

Methods gain workflow efficiencies over other high abundance depletion and in-solution digestion workflows.

Swapan Roy, Matthew Kuruc. "The Functional Subproteomes of Serpin Protease Inhibitors are Now Open for LC-MS Biomarker Discovery." MOJ Proteomics Bioinform (2016).

Demonstrates utility of AlbuVoid™ & AlbuSorb™ to satisfy investigations of serum SERPINs.

David L. Wang, et al. "Identification of potential serum biomarkers for breast cancer using a functional proteomics technology." Biomarker Research (2017).

AlbuVoid™ was necessary to enrich low-level proteases to detectable levels for enzyme activity detection.