Caspases Assay Kits

 

 

Caspases는 진화적으로 보존된 단백질 군으로, programmed cell death (apoptosis) 에 필수적이며, 이 과정의 initiator 와 executioner 로 작용합니다. 이들은 세포 항상성(cellular homeostasis)를 유지하고, 세포 생존과 사멸 사이의 미세한 균형을 조절하는 데 중요한 역할을 합니다.

 

이 단백질 군은 세 가지 기능적 그룹으로 나뉩니다:

- Initiator caspases :        caspase 2, 8, 9, 10

- Executioner caspases :    caspase 3, 6, 7

- Inflammatory caspases :  caspase 1, 4, 5, 11, 12

 

Caspase biology 의 세부 사항을 이해하는 것은 therapeutic interventions 에 큰 영향을 미칩니다. 이러한 효소를 표적으로 삼는 것은 비정상적인 세포 생존 또는 사멸(aberrant cell survival or death)이 특징인 질환 치료를 위한 방법을 제공합니다. 이는 정밀 의학(precision medicine)의 미래를 엿볼 수 있는 가능성을 제시합니다.

 

 

 

 

제품 리스트

Green Fluorescent FAM-VAD-OPH I in vitro poly Caspase Apoptosis Detection Reagent (6354)

 

Green Fluorescent FAM-VAD-OPH II in vitro poly Caspase Apoptosis Detection Reagent (6355)

 

Green Fluorescent FAM-DEVD-OPH in vitro caspase-3/7 Apoptosis Detection Reagent (6356)

 

Red Fluorescent SR-VAD-OPH in vitro Poly Caspase Apoptosis Detection Reagent (6357)

 

Green Fluorescent FAM-FLICA® Caspase-8 (LETD) Assay Kit (910)

 

Near-Infrared DyLight® 690 Tracer in vivo Active Caspase (VAD) Assay (9112)

 

Near Infrared DyLight® 690 Free Dye Control Assay (9113)

 

Near-Infrared DyLight® 747 Tracer in vivo Active Caspase (VAD) Assay (9114)

 

Near Infrared DyLight® 747 Free Dye Control Assay (9115)

 

Far-Red Fluorescent FLICA® 660 Poly (active) Caspase (VAD) Assay Kit (9120)

 

Far-Red Fluorescent FLICA® 660 Caspase-1 (YVAD) Assay Kit (9122)

 

Far-Red Fluorescent FLICA® 660 Caspase-3/7 (DEVD) Assay Kit (9125)

 

Green Fluorescent FAM-FLICA® Caspase-9 (LEHD) Assay Kit (913)

 

Pyroptosis/Caspase-1 Assay - Green Fluorescent (9146)

 

Red Fluorescent SR-FLICA® Caspase-8 (LETD) Assay Kit (9150)

 

Pyroptosis/Caspase-1 Assay - Far Red Fluorescent (9158)

 

Green Fluorescent FAM FLICA® Caspase-1 (WEHD) Assay Kit (9162)

 

Red Fluorescent SR-FLICA® Poly (active) Caspase (VAD) Assay Kit (917)

 

Green Fluorescent FAM-FLICA® Caspase-2 (VDVAD) Assay Kit (919)

 

Green Fluorescent Poly (active) Caspase FAM FLICA® Assay Kit (FAM-VAD-FMK) (92)

 

Green Fluorescent FAM-FLICA® Caspase-10 (AEVD) Assay Kit (923)

 

Red Fluorescent SR-FLICA® Caspase-3/7 (DEVD) Assay Kit (932)

 

Magic Red® Fluorescent Caspase-3/7 Assay Kit (936)

 

Green Fluorescent FAM-FLICA® Caspase-3/7 (DEVD) Assay Kit (94)

 

Green Fluorescent FAM-FLICA® Caspase-6 (VEID) Assay Kit (96)

 

Red Fluorescent SR-FLICA® Caspase-9 (LEHD) Assay Kit (961)

 

Green Fluorescent FAM-FLICA® Caspase-1 (YVAD) Assay Kit (98)

 

Green Fluorescent FAM In vivo Poly (active) Caspase (VAD) Assay (981)

 

Red Fluorescent SR In vivo Poly (active) Caspase (VAD) Assay (983)

 

Apo 3/7 HTS Assay Kit (APO200-4)

 

Apo Active FITC - Caspase 3 Detection Kit (FAB200-2)

 

Dual Poly Caspase and Mitochondrial Membrane Potential Assay Kit (MITCAP100-2)

 

Dual Caspase 3/7 and Mitochondrial Membrane Potential Assay Kit (MITCAP200-2)

 

Dual Caspase 1 and Mitochondrial Membrane Potential Assay Kit (MITCAP600-2)

 

Apo Active PE - Caspase 3 Detection Kit (PAB200-2)

 

 

Cell Viability Catalog

Cell Viability Product Advantages Catalog