RarePlex® CTC Panel Kits for enumeration    

 

Immunofluorescent detection of circulating tumor cells (CTCs) for enumeration and 

are designed for the RareCyte blood-to-result circulating tumor cell analysis platform.

 

Enumeration Panel Kits identify EpCAM positive or negative epithelial circulating tumor cells, contain a nuclear dye and a panel of antibodies and reagents for detection of CD45 (to exclude WBC), Cytokeratin, and EpCAM in a 3-channel format.

 

All RarePlex CTC Panel Kits are extensively validated and held to high standards for sensitivity, specificity, and precision. Kits are available for Leica® BOND RX or Ventana® DISCOVERY® ULTRA automated staining systems. Panel Kits are ideal for use in large, multi-center circulating tumor cell enumeration trials.

 

 

 

 

RareCyte’s deployable platform for circulating tumor cell analysis:

 

  •  A clinical research laboratory can perform the entire process in their own lab

  •  Platform produces accurate and highly reproducible results

  •  Convenient pause points in workflow enable shipping between sites

  •  Flexibility in sample processing – A site can process AccuCyte slides and/or perform staining and analysis

  •  Leverage worldwide network of contract research organizations

 

With a 3-channel Panel Kit for enumeration, you have the flexibility to create custom assays by adding up to two biomarkers with Developer Kits. 

 

RareCyte RarePlex CTC Panel Kit, Manual Staining (DAPI)      24-1221-004

This 3-channel kit (Version: 0700-MA) detects epithelial CTCs. The kit contains the nuclear dye DAPI and antibodies detecting CD45 (to exclude WBC), CK and EpCAM. Samples are stained manually and imaged on CyteFinder®. 

RareCyte RarePlex CTC Panel Kit, Manual Staining(Hoechst)      24-1277-004

This 3-channel manual staining kit (Version: 1200-MA) detects epithelial CTCs. The kit contains a nuclear dye and antibodies detecting CD45 (to exclude WBC), CK and EpCAM. Samples are stained manually and imaged on CyteFinder®.

 

RareCyte RarePlex CTC Panel Kit, Leica (SYTOX)      24-1245-001

This 3-channel kit (Version: 0900-LB)detects epithelial CTCs. The kit contains a nuclear dye and antibodies detecting CD45 (to exclude WBC), CK and EpCAM. Samples are stained by Leica® BOND® RXstaining system and imaged on CyteFinder®.

 

RareCyte RarePlex CTC Panel Kit, Ventana (SYTOX)      24-1245-002

This 3-channel kit (Version: 0900-VB) detects epithelial CTCs. The kit contains a nuclear dye and antibodies detecting CD45 (to exclude WBC), CK and EpCAM. Samples are stained by Ventana® DISCOVERY® ULTRA and imaged on CyteFinder®.

 

RareCyte RarePlexCTC Panel Kit, Leica (Hoechst)      24-1277-001

This 3-channel kit (Version: 1200-LB) detects epithelial CTCs. The kit contains a nuclear dye and antibodies detecting CD45 (to exclude WBC), CK and EpCAM. Samples are stained by Leica® BOND® RX and imaged on CyteFinder®.

 

RareCyte RarePlex CTC Panel Kit, Ventana (Hoechst)      24-1277-002

This 3-channel kit (Version: 1200-VA) detects epithelial CTCs. It contains a nuclear dye and antibodies detecting CD45 (exclude WBC), CK & EpCAM. Samples are stained by Ventana® DISCOVERY® ULTRA and imaged on CyteFinder®.

 

RarePlex 1108-LA CTC Staining Kit, 200 slides     24-1234-001

4 channel, custom CTC assay for DLL3 detection.

 

 

RarePlex SHP77 Control Slide, 10-Pack      24-1236-000

Batch control slides to be stained, scanned, and reviewed alongside experimental slides. Slides contain monolayer of buffy coat and spiked-in SHP77 cells.

 

RareCyte RarePlex CTC Negative Control Slide, 10-Pack      24-1278-000

Batch control slides to be stained, scanned, and reviewed alongside experimental slides. Slides contain a monolayer of buffy coat from healthy normal donors.Slides are negative for circulating tumor cells (CTCs).

 

RareCyte RarePlex BT-474 spike-in CTC Control Slide, 10-Pack     24-1247-000

Contain monolayer of buffy coat & spiked-in BT-474 cells. Compatibility: 24-1257-002,24-1245-002, 24-1245-001, 24-1277-002, 24-1277-001, 24-1277-004, 24-1280-002, 28-1001-481, 28-1001-401, 28-1001-402, 28-1001-482

 

 

RareCyte RarePlex Cell Discovery Kit, Leica      24-1294-001

This 3-channel kit (Version:09-LB) allows custom panel development for detecting CTCs that do not express epithelial markers, and other rare cells.Kit has nuclear dye and reagents for the 647 nm and 800 nm. Samples are stained by a Leica® Bond® Rx.

 

RarePlex Cell Discovery Biomarker: anti-Hu CD45-Biotin-A-L, 200-Slides      42-1212-001

This conjugated antibody can be used with the Cell Discovery Kit on the Leica Bond Rx to detect CD45 protein of human origin in the 800 channel.

 

RarePlex Cell Discovery Biomarker: anti-Hu CK-DIG -A-L, 200-Slides      42-1210-001

This conjugated antibody can be used with the Cell Discovery Kit on the Leica Bond Rx to detect a variety of Cytokeratin proteins of human origin in the 647 channel.

 

RarePlex Cell Discovery Biomarker: anti-Hu EpCAM-DIG -A-L, 200-Slides      42-1211-000

This conjugated antibody can be used with the Cell Discovery Kit on the Leica Bond Rx to detect the Epithelial Cell Adhesion Molecule (EpCAM) protein of human origin in the 647 channel.

 

RarePlex Cell Discovery Biomarker: anti-Ms CD45-Biotin-A-L, 200-Slides      42-1213-001

This conjugated antibody can be used with the Cell Discovery Kit on the Leica Bond Rx to detect CD45 protein of mouse origin in the 800 channel.Use this antibody if your sample is derived from a mouse model.

 

 

RareCyte CyteMount Mounting Media      42-1056-000

A solutionthat enables a coverslip to adhere to a microscope slide 30 ml.