미세유체 칩 기반 마이크로파티클/ 나노파티클 합성 시스템
Microfluidic Microparticle/Nanoparticle Synthesis System
Micro/Nanoparticles, especially polymer nanoparticles, have shown great potential for biomedical applications in a variety of fields such as pharmaceutical industries like drug delivery, and biosensing because of its excellent properties.
Micro/Nanoparticle synthesis by microfluidic technology presents advantages over the conventional batch synthesis processes due to its capacity in better
uniformity in size and shape. For example, in the drug delivery field, nanoparticles can be synthesized from block copolymers such as PLGA and liposomes, which are the most commonly used biodegradable materials for the delivery of both hydrophilic and hydrophobic compounds.
• Compact and portable design
• Precise and accurate pressure/flow output
• Fast response time
• Controllable liquid flow rate output with external liquid flow sensors
• Standard connection. Easy connect to other components
• OEM service and module integration available
시스템 구성(System Contents):
• PG-MFC controller, 1 pc
• Reservoir kit, 15ml, 2 sets
• Liquid flow sensor (optional)
• Microfluidic mixer chips, 2 pcs
• Tubings and Fittings
• High-speed imaging system with illuminations (optional)
합성 용 미세유체 칩 (Microfluidic Chips for Synthesis):
PreciGenome offers a variety of microfluidic chips in different materials to meet most of our customers' application requirements for microparticles and nanoparticles synthesis.
Microfluidic mixer chips are usually for nanoparticles synthesis. Droplet generation chips are the most frequently used for microparticles synthesis.
Three types of materials, including polymers, glass and silicon, are commonly used to fabricate microfluidic chips. Material of the chip is selected depending on the application requirements, including chip design, types of solvent or reagent used for experiment, needs of the application, budget, and fabrication time,etc.
합성 시스템 어플리케이션(Synthesis System Applications) :
Drug Delivery (PLGA, Lipid & Liposome)
Droplet microfluidics enables useful platforms for drug delivery vehicles and drug molecules as novel functional materials. Because of uniform size, monodisperse size distribution, and desired properties, droplet microfluidics demonstrates promising potential for the production of complex drug systems.
Droplet-based microfluidics has become an important method for chemical synthesis. Droplets are able to act as individual reactions, which are free from contamination from outside. Meanwhile, it also offers benefits of high throughput, small reagent volumes, low cost, portability, a high degree of synthetic control, rapid reaction, etc.
Microparticle and Nanoparticle Synthesis
Advanced particles and particle-based materials, such as polymer particles, microcapsules, nanocrystals, and photonic crystal beads can be synthesized by the droplet generation system. The droplet generation system is also able to synthesize nanoparticles, like colloidal CdS and CdS/CdSe core-shell nanoparticles.
Gel Particle Synthesis
In the last decade, the gel particles (hydrogels, microgels, and nanogels) has been an area of interest for many researchers and industries. Because of high throughput, mono-dispersity of particles, and low cost, droplet-based microfluidic systems have been widely used for synthesizing these hydrogel particles.
PLGA Nanoparticle Synthesis
Drug-loaded PLGA nanoparticles (NPs) can be synthesized by our system. PLGA NPs synthesis in continuous flow microfluidics by the nanoprecipitation process.
Liposome Nanoparticle Synthesis
Precise lipid and liposome synthesis by microfluidic mixing methods. Efficient method for generating nanoparticles for targeted drug or nutrient delivery
PLGA Drople-based Microparticle Synthesis
PLGA Microparticles are produced via template droplets that turn into microparticles by solvent evaporation. Easy to generate PLGA droplets. It includes everything you need for synthesis.
PG-SYN Precigenome micoparticle/nanoparticle synthesis system: three different packages
1) Microfluidic pressure controller (choose model);
2) High speed imaging system (optional);
3) MIcrofluidic reservoir kits (2 of 15mL)
4) Fittings, connectors, and tubings;
5) A mixing chip.
PG-SYN-8-HSV includes PG-MFC-8CH and high speed imaging system
PG-SYN-8 includes PG-MFC-8CH
PG-SYN-LT2 includes PG-MFC-LT-2CH