Enzyme Libraries

Directed evolution is becoming a widely used technique for modifying or 

enhancing enzyme performance. Ultimately, the success of directed protein

evolution experiments hinges on the efficiency of the methods used to 

screen libraries for mutants with properties of interest. Recent advances in 

library design, and methods of random mutagenesis, combined with new 

screening and selection tools, continue to push forward the potential of 

directed evolution. The power of cell surface-display techniques for the 

selection of novel enzymes is greatly improving the library size and 

hence the sequence space that can be searched. 

 

•  Imine Reductase

•  Threonine Dehydrogenase

•  Leucine Dehydrogenase

•  Lactate Dehydrogenase

•  Phenylalanine Dehydrogenase

•  Monoamine Oxidase

•  Formate Dehydrogenases

•  Glucose Dehydrogenases

•  Pig Liver Esterase 

•  Epoxide Hydrolases

•  D-amino Acid Dehydrogenase

•  Alcohol Oxidase

•  Cytochrome P450 Monooxygenase

•  Aldolase

•  Nitro Reductases

•  Oxynitrilases

•  Ene Reductases

•  Nitrilases

•  Nitrile Hydratases

•  Amidases

•  Ketone reductase