Enzyme for Antibody Research
Nowadays, antibodies have become the most popular studied category for their functions in diseases and drugs. Although the research has been improved step by step from chimeric antibodies to human antibodies, there are still many challenges in the area, such as structure characterization and conjugation. Focused on analysis and modification of peptides and glycans, Creative Enzymes offers high quality enzyme products to support the most advanced research on antibodies.
• Full range of products cover IgG proteases and IgG glycosidase
• Highly site- and sequence-specific
• Innovative and unique enzymes
• Short incubation time, 30 min to 2 h
The main function of IgG proteases is to digest IgG to generate Fab and Fc fragements for subsequence analysis or modification purposes.
|NATE-1599||Mouse IgG2a, IgG3|
|NATE-1600||All subclasses IgG (human, mouse, rat, goat and sheep)|
We also have immobilized enzymes for IgG and IgM fragmentation.
|NATE-1866||IgG / IgM|
The main function of IgG glycosidases is to hydrolyze glycans from the Fc region.
|NATE-1603||Complex N-linked glycans in the native IgG Fc region|
|NATE-1604||All glycoforms on IgG, including high-mannose|
|NATE-0603*||High mannose, hybrid, and complex N-glycans|
Arginine specific protease digests proteins C-terminal to arginine residues and is used for antibody characterization.
|NATE-1602||Arg-X motifs in peptides and proteins|
Antibody Labeling and Conjugation
Creative Enzymes's unique technology for covalent conjugation of a label to the Fc domain of the antibody. Besides, enzymes were developed and optmized as labels for antibody labelling.
|Cat. No.||Product Name|
|NATE-0550||Native Horseradish Peroxidase|
|NATE-0054||Native Calf Alkaline Phosphatase|
|NATE-0311||Native Aspergillus niger Glucose Oxidase|
|DIA-189||Native Escherichia coli β-Galactosidase|