Liposomal Ciprofloxacin

 

Drug-loaded liposomes

 

 

 

The PEGylated and non-PEGylated liposomal ciprofloxacin contains 1 mg/ml ciprofloxacin. 

The PEGylated liposome is composed of hydrogenated soy phosphocholine (HSPC), 1,2-distearoylsn- glycero-3 phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000) and cholesterol at a mass ratio of HSPC:DSPE:Cholesterol of 3:1:1. 

The Non-PEGylated liposome is composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol at a mass ratio of DPPC:cheleterol of 1.9:1. The ciprofloxacin encapsulation percentage is more than 95 %. The average size of liposomes is about 80 nm with poly dispersity index (dpi) of 0.1.

 

 

 

 

 

 

 

 

 

 

DPPC Liposomal Ciprofloxacin- 2 mg (Catalog No. DPPC002CP) 

Contains 2 ml of liposomal ciprofloxacin at concentrations of 1 mg/ml ciprofloxacin and 23 mg/ml of lipids composed of HSPC and cholesterol.

 

 

 

 

PEGylated HSPC Liposomal Ciprofloxacin- 2 mg (Catalog No. PHPC002CP) 

Contains 2 ml of liposomal ciprofloxacin at concentrations of 1 mg/ml ciprofloxacin and 18 mg/ml of lipids composed of DSPE-PEG2000, HSPC and cholesterol.