Cluster of Differentiation

The clusters of differentiation (CD antigens) are a diverse group of surface glycoproteins with a multitude offunctions, providing the interface between a cell and the external environment that includes other cells.Serving as receptors and ligands, they regulate cell signaling and adaptive immunity and are widely used inimmunology, oncology, and stem cell biology research. Therefore, the roles of CD antigens are critical inmany research fields, including immunotherapy, tumor-associated physiology, and new drug targets.

Clinical Application of CD antigens : 

•  Analysis of leukaemia and lymphomas

•  Detection of minimal residual disease

•  Stem cell enumeration

•  Solid organ transplantation

•  Immunodeficiency disease

•  HIV infection

•  Paroxysmal nocturnal haemoglobinuria

•  Immunotherapy

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