Liposomes for Membrane Protein Reconstitution

 

 

 

Reconstitution membrane proteins is often accomplished by incubation of purified membrane proteins with liposomes in the presence of detergent. The detergent is removed after the incubation by a hydrophobic column or extensive dialysis. The dialysis method can only be applied to detergents with a high CMC value. 

The following liposomes are currently available for membrane protein reconstitution:

 

 

 

HSPC: Cholesterol: DSPG-PEG2000 liposome (Catalog No. HSCP010) 

Contains 10 ml of 10 mg/ml liposome composed of HSPC: Cholesterol: DSPG-PEG2000 (m/m, 3:1:1).

 

 

 

DPPC: Cholesterol liposome (Catalog No. DPC010) 

Contains 10 ml of 10 mg/ml liposome composed of DPPC: Cholesterol (m/m, 1.9:1).