PEGylated Liposomes w/ Ammonium Sulfate

 

Ready-to-load liposomes for drug delivery

 

 

 

 

Liposomal drug formulations provide great opportunities of improving the drug efficacy and toxicity profiles. Drug molecules with amine groups such as doxorubicin, daunorubicin, topotecan and irinotecan etc. can be loaded by ammonium-based pH gradient. 

The Ready-toload PEGylated HSPC Liposomes with Ammonium Sulfate (Catalog No PHPC200AS) are high quality PEGylated liposomes that are ready to load drug molecules containing amine groups. The drug loading process is completed in about 3 hours after mixing the drug with the liposomes.

 

 

 

 

 

 

 

 

Ready-to-load PEGylated HSPC Liposomes with Ammonium Sulfate (Catalog No. PHPC200AS)

 

Includes 10 ml liposomes with 20 mg/ml lipid concentration. The mass ratio of lipids is HSPC: cholesterol: DSPE-PEG2000 = 3:1:1. The concentration of ammonium sulfate encapsulated within the liposomes for drug loading is 200 mM. The buffer is 10 mM histidine, pH 6.5, 9.2 % sucrose. Liposomes are stored in a 2°C to 8°C refrigerator. DO NOT freeze liposomes.