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AlbuSorb™ PLUS
제품명: AlbuSorb™ PLUS
용도: Albumin & IgG Removal Kits
메이커: Biotech Support Group
카달로그:


소개


AlbuSorb™ PLUS      Albumin + IgG Depletion Kit From Serum or Plasm

 

•  > 400 µg total serum protein mass 

   (> 85% Albumin, >85% IgG depleted) from 25 µl serum prepAlbuSorb™ PLUS_#1.PNG

•  Affinity-type equivalence, virtually no cross-reactivity with other 

   proteins

•  Disposable, no column regeneration or cross-contamination

•  Combines unique bead technology, not based on Blue-dye 

   affinity, with optimized Protein A

•  Mild conditions maintains structural integrity and simple transfer 

   to secondary analysis

•  The albumin and IgG depleted filtrate retains the enzymatic and 

   biological activity, along with enrichment of extracellular vesicle 

   (exosome) cargo

•  Suitable for immunoassay, Western blot, 1 & 2D Electrophoresis, 

   enzyme assay, LC-MS

•  Tested species include human, sheep, bovine, rabbit, mouse, rat 

 

Poly-electrolytes are polymers with repeating units of stationary charges. AlbuSorb™ comes from a class of solid-phase, or surface-based, elastomeric poly-electrolytic surfaces that bind proteins through an empirically derived chemistry combining elements of polymer composition, cross-linking architecture and charge properties. AlbuSorb™ combines with an optimized immobilized Protein A to create AlbuSorb™ PLUS. Unlike immuno-affinity, the surfaces utilized are disposable eliminating cycle to cycle variance and cross-contamination. AlbuSorb™ PLUS is supplied as a powder. Simply weigh, centrifuge and/or filter, and recover the albumin depleted serum in the supernatant.

 

 

☞  Click here to view AlbuSorb™ PLUS Product Sheet 

 


  AlbuSorb™ PLUS_프로토콜.PNG

사양

AlbuSorb™ PLUS_사양.PNG

주문정보

AlbuSorb™ PLUS_주문정보.PNG

관련자료

<Application Report >


AlbuVoid™ PLUS & AlbuSorb™ PLUS - Evaluating Different Windows of Observation Solves The Many Challenges of Serum Proteomics

AlbuSorb™ Product Extension combines Albumin and Immunoglobulin Depletion in a Consumable Format 


<References> 


Cerebrospinal Fluid 

Gwenael Pottiez, Pawel Ciborowski. Proteomic Profiling of Cerebrospinal Fluid Expression Profiling In Neuroscience Neuromethods.2012;64:245-270 


Synovial fluid

Happonen KE, Fürst CM, Saxne T et al. PRELP protein inhibits the formation of the complement membrane attack complex. Journal of Biological Chemistry.2012;287(11):8092-100 


Serum

Zheng H, Soherwardy A, Roy S, Kuruc M, Avadhani S. AlbuVoid™ Enrichment & Antibody Depletion – Tackling the Challenges of Serum Proteomics Part II. Poster reprint first presented at 26th International Molecular Med TRI-CON, March 10-15, 2019, San Francisco, CA USA

Roy, Swapan, and Matthew Kuruc. "Methods to Monitor the Functional Subproteomes of SERPIN Protease Inhibitors." Functional Proteomics. Humana Press, New York, NY, 2019. 41-54.

Dr.Swapan Roy; Amenah Soherwardy; Ravish Amin; Matthew Kuruc Biotech Support Group LLC, Monmouth Junction, NJ - Application ReportAlbuSorb™ Product Extension combines Albumin and Immunoglobulin Depletion in a Consumable Format

Holmberg R, Refai E, Höög A.Lowering apolipoprotein CIII delays onset of type 1 diabetes. Proceedings of the National Academy of Sciences.2011;108(26):10685-9. 

Tang MX, Ogawa K, Asamoto M. Effects of Nobiletin on PhIP-Induced Prostate and Colon Carcinogenesis in F344 Rats Nutrition and Cancer.2011;63(2):227-33 

Holmberg, Rebecka Apolipoprotein CIII and Ljungan virus in diabetes 2010. Doctoral Thesis

Lu Q, Zheng X, McIntosh T Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs. Analytical Chemistry.2009;81(21):8715-23 


Urine

Zubiri, Irene, et al. "Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis." Journal of proteomics 96 (2014): 92-102. 


Patent

Berggren, Per Olaf, Yang, Shao-Nian. 2012. Methods For Treating And/Or Limiting Development Of Diabetes.U.S. Patent 20120328630 Kind Code: A1, filed June 25, 2012, and issued December 27, 2012.