Product
소개
HemoVoid™ Hemoglobin Variant Enrichment from Blood
Purification & Enrichment Of Hemoglobin From Blood For Hemoglobin Variant Research
• Hemoglobin enrichment from fresh or frozen blood and dried blood spot/blood card etc.
• Enriched hemoglobin voids in flow-through >98% pure, with <30 minute bind/wash/elute protocol
• Disposable, cost-effective and high-throughput.
• Mild buffer condition maintains tertiary structure and simple transfer to secondary analysis
• Enriches hemoglobin from diverse species including human, sheep, mouse, goat, rat, etc.
• Enriched/purified hemoglobin can be studied for variant research and other research applications.
• Eluted fractions contains hemoglobin depleted proteins which can be used for LC-MS, proteomic studies
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References
P. falciparum clone 3D7 cultured in human erythrocytes Lasonder E, Green JL, Camarda G, Talabani H, Holder AA, Langsley G, Alano P. The Plasmodium falciparum schizont phospho-proteome reveals extensive phosphatidylinositol and cAMP-Protein Kinase A signalling. J Proteome Research. 2012; Red Blood Cell Lysate Katja Walpurgis, Maxie Kohler, Andreas Thomas et al.Validated hemoglobin-depletion approach for red blood cell lysate proteome analysis by means of 2D-PAGE and Orbitrap MS.Electrophoresis.2012; Mizukawa, B., George, A., Pushkaran, S. et al. Cooperating G6PD mutations associated with severe neonatal hyperbilirubinemia and cholestasis.Pediatric Blood Cancer.2011;56: 840-842. Sudha Neelam, David G Kakhniashvili, Stephan Wilkens et al. Functional 20S proteasomes in mature human red blood cells Experimental Biology and Medicine.2011;236:580-591 |