Protein Kinases Landscape (Large Format PEP) 

Complete kit for the systematic analysis of protein kinases from 

a proteome such as cell lysate, tissue or microorganisms

Proteins play essential roles in numerous biological processes, protein kinases is a large family of enzymes involved in many signal transduction pathways, there are over 500 protein kinases in the human genome and many of them play important roles in cancer and metabolic diseases. This Protein Kinase Connect kit will allow the systematic analysis of the protein kinases in any proteome of interest and build the 3-D landscape of this important enzyme family. The information can be used for the further understanding of the biochemical process, identification of novel drug targets and study drug safety among the potential applications. 

The small format PEP has 384-wells matching the current 384-well microplate dimension for ease of sample processing. For the large format PEP, the plate is composed of 4 384-well PEP thus have 1536 wells.In both the large and small format PEP, a membrane with molecular cut off of 6,000 Dalton is attached that will allow the electric current and small charged molecules to pass through but collect proteins with molecular weight large than 6,000 Dalton in the PEP wells. 

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