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TUNR Flexible Gene Editing for Plasmid-Delivered Transgenes
제품명: TUNR Flexible Gene Editing for Plasmid-Delivered Transgenes
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메이커: Canopy Biosciences
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소개

 

TUNR Flexible Gene Editing for Plasmid-Delivered Transgenes

 

The TUNR Plasmid-Delivered Transgenes kit allows you to control the expression of a transgene. Simply transfect your cells with one of our four plasmids containing your gene under the control of TUNRs of different strengths.

 

 

사진.PNGThe TUNR Flexible Gene Editing System from Canopy Biosciences allows you 

to precisely control the expression of your gene of interest. Our kits are 

custom-designed for your project and include everything you need to tune 

gene expression in your favorite cell line.

  

•  Precisely tune gene expression from 100% all the way down to complete 

   knockout 

•  Model ranges of gene expression reflecting diversity in patient populations 

•  Control endogenous gene expression–eliminate artifacts from ectopic 

   expression 

•  Knockdown essential genes where knockout would result in lethality

 

 

How the TUNR Flexible Gene Editing System works


Introduction of the TUNR polyA track results in reduced gene expression.The TUNR Flexible Gene Editing System leverages the CRISPR-Cas9 system for targeted integration of a polyA track at a preciselocation within the targeted gene.


License

Canopy Biosciences holds the exclusive license for TUNR from Washington University and Johns Hopkins University.

 

WUSTL logoJohns Hopkins logo 


주문정보

TUNR0001          TUNR Plasmid Delivered Transgene Kits          1 kit

Controls             Empty vector control, eGFP/Neo                  Option

Controls             Empty vector control, Neo                         Option


 

" The TUNR kit for Plasmid-Delivered Transgenes contains everything you need to get started with TUNR technology " 

 

Including :    

 • Plasmids, containing one of four TUNR sequences and your target gene   

     -  TUNR-L Lower level of repression 

     -  TUNR-ML Lower level of repression 

     -  TUNR-MH Higher level of repression 

     -  TUNR-H Higher level of repression 

 • Forward and reverse primers  

 

Required Information 

1.  Species (Ex: Human, Mouse, Rat, Other) 

2.  Gene ID 

3.  Fluorescent: eGFP or No fluorescent marker 

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