Product
소개
TUNR Flexible Gene Editing for Targeted Transgenes
The TUNR Targeted Transgenic kit enables you to insert your gene of interest under TUNR control into the AAVS1 locus. AAVS1 is a “safe harbor”—a safe place to integrate transgenes, allowing predictable expression from a locus known not to alter the expression of other genes or have otherwise deleterious effects on the cell.
• Precisely tune gene expression from 100% all the way down to complete
knockout
• Model ranges of gene expression reflecting diversity in patient populations
• Control endogenous gene expression–eliminate artifacts from ectopic
expression
• Knockdown essential genes where knockout would result in lethality
How the TUNR Flexible Gene Editing System works
License
Canopy Biosciences holds the exclusive license for TUNR from Washington University and Johns Hopkins University.
주문정보
TUNR0005 TUNR Targeted Transgene Kits 1 kit
Controls Empty Vector Control Option
Controls Positive Contorl, eGFP Option
The TUNR Targeted Transgenic kit contains everything you need to integrate your gene of interest,
under TUNR control, into the AAVS1 locus:
• crRNA targeting the AAVS1 locus
• tracRNA
• Cas9 protein
• Plasmids, containing one of two TUNR sequences and your target gene, flanked by homology arms to the AAVS1 locus
- TUNR-ML Lower level of repression
- TUNR-H Higher level of repression
• Forward and reverse primers
Required Information
1. Species: Human (AAVS1) or Mouse (Rosa26)
2. Gene ID
관련자료
References