Product
소개
TUNR Flexible Gene Editing for Endogenous Genes
The TUNR Flexible Gene Editing System for Endogenous Genes allows you to generate four cell lines or animal models with four different levels of knockdown of your endogenous gene of interest.
The TUNR Flexible Gene Editing system allows for the modulation of expression of virtually any endogenous gene. The system leverages CRISPR-Cas9 genome editing technology to integrate TUNR sequences of varying strengths at a precise location within your gene of interest.
• Precisely tune gene expression from 100% all the way down to complete
knockout
• Model ranges of gene expression reflecting diversity in patient populations
• Control endogenous gene expression–eliminate artifacts from ectopic expression
• Knockdown essential genes where knockout would result in lethality
How the TUNR Flexible Gene Editing System works
License
Canopy Biosciences holds the exclusive license for TUNR from Washington University and Johns Hopkins University.
주문정보
TUNR0008 TUNR Endogenous Gene Kits 1 kit
Add-ons CRISPR validation Option
The kit contains everything you need to alter the expression of your gene, including:
• crNA designed to specifically target the precise location to integrate the TUNR sequences in your gene of interest • tracRNA
• Cas9 protein
• Oligonucleotides, containing one of four TUNR sequences flanked by homology arms to your gene of interest
- TUNR-L Lower level of repression- TUNR-ML Lower level of repression
- TUNR-MH Higher level of repression
- TUNR-H Higher level of repression
• Forward and Reverse Primers
Required Information
1. Species (Ex: Human, Mouse, Rat, Other)
2. Gene ID
관련자료
References