Product
소개
micro ViscoStar®
Online differential viscometer for UHPLC
A highly sensitive, on-line differential viscometer used with SEC-MALS-IV to determine the size and conformation of polymers, proteins and peptides separated by UHPLC. The microViscoStar™ incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's microDAWN™ light scattering and microOptilab™ refractive index detectors for UHPLC.
View the webinar "Development of a New Online Micro-Viscometer for APC and UHPLC Applications".
To learn about the technological breakthroughs implemented in the microViscoStar, download "ViscoStar: Innovations in Online Viscometry for GPC".
Another path to polymer and protein characterization: SEC-MALS-IV
When coupled with UHPLC size-exclusion chromatography and a compatible concentration detector such as the Optilab UT-rEX, themicroViscoStar
derives the intrinsic viscosity (IV) of polymers, rapidly and with minimal sample and solvent consumption. An inherently valuable physico-chemical
property in itself, IV is best utilized together with molar mass information from a µDAWN multi-angle light scattering (SEC-MALS-IV) to derive the
hydrodynamic radius, conformation, and branching ratio of a macromolecule in solution.
Key benefits of the microViscoStar
SEC-IV without MALS?
Yes, as much as we love MALS for optimal polymer analysis, it's true thatthere are occasions when it just won't fit the bill.
Universal calibration is a parallel technique to SEC-MALS for determining molecular weight, commonlyused to characterize linear polymers.
While universal calibration overcomes some of the problematic issuesassociated with column calibration by reference molecules,
it does not account for non-ideal column behaviorcaused by chemical solute-column interactions or hyperbranching.
Universal calibration is particularly-well suited to replace MALS for:
• Strongly fluorescent polymers
• Weakly-scattering polymer/solvent systems with very low dn/dc values
The Mark-Houwink-Sakurada relationship makes use of empirical relationshipsbetween intrinsic viscosity and molar mass, specific to each polymer
and solvent, to estimate molar massfrom SEC-IV measurements. Of course, the best way to determine MHS coefficients is to measure them using
SEC-MALS-IV and ASTRA!
사양
액세서리
Orbit - The Orbit helps conserve mobile phase by programmatically directing the solvent to either a waste bottle or back to the solvent reservoir.
Solaris - Prevents growth of bacteria, fungi or algae in solvents with high efficiency and protects your system from down-time due to contamination.
관련자료
Viscometry-only
The microViscoStar may be used with any* UHPLC-SEC system, including Waters Acquity APC™, as long as the sample does not need to be heated above 70°C in order to flow through 0.005" (0.125 mm) i.d. tubing. Combine with an Optilab UT-rEX for the concentration measurements needed in viscometry calculations.ASTRA supports Universal Calibration as well as molar mass determination using Mark-Houwink-Sakurada coefficients.
SEC-MALS-IV
Combine the microViscoStar with a µDAWN MALS detector for an even more versatile combination that can determine Mark-Houwink-Sakurada parameters and other measures of conformation and stability. ASTRA handles all the calculations you need for full characterization of your polymers.