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[항생제 내성] 항생제 내성과 새로운 세균성 약물 유출 펌프 탐색 (Antibiotic Resistance and the Hunt for Novel Bacterial Drug Efflux Pumps)
인성크로마텍(주)
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Date : 2022.04.14 |
항생제 내성과 새로운 세균성 약물 유출 펌프 탐색 Antibiotic Resistance and the Hunt for Novel Bacterial Drug Efflux Pumps • Presented by : Dr. Ian Paulsen, Director, ARC Centre of Excellence in Synthetic Biology, Macquarie University Sydney NSW Australia • Presented Live : December 09, 2021
Webinar Topics Include
• Transcription and TraDIS were used to identify membrane proteins of unknown function that might potentially be new multidrug efflux pumps • Candidate genes were cloned and expressed in E. coli and Biolog Phenotype MircoArrays™ 11-20 were used to identify putative substrates • Transport assays were used and we discovered three putative novel drug efflux pump families • Biochemical and biophysical assays of the purified proteins confirmed their interaction with substrates
Antibiotic Resistance and the Hunt for Novel Bacterial Drug Efflux Pumps from Biolog on Vimeo. |