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[점도] 생체의약품
인성크로마텍
Date : 2019.11.26
분류 : 생체의약품

 

Where does viscosity fit when it comes to the Pharmaceutical and Biotechnology Industry?

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Protein-based drugs are the fastest growing class of drugs for the treatment of many diseases in humans, ranging from cancer to Alzheimer’s disease. Accurate viscosity values of proteins are essential in understanding behavior, designing delivery systems, and accurately determining particle size/hydrodynamic radius.  

VROC® powered viscometers deliver accurate and reliable viscosity results that are required to understand behaviors of antibodies and other proteins. By applying a wide range of viscosities and shear rates, you can gain a full length range of insight into your proteins.

Remember VROC® technology : 

  • 1.  Smallest sample volumes
  • 2.  Direct shear rate control
  • 3.  First principle or true viscosity   
  •  

Check out all of our application notes separated into major topics:

 

 

# 1.  Formulation 


Protein Formulation Requires Stability & Efficacy

Working with various protein candidates, buffers, adding excipients, etc, check out the application notes that we have published that are important to formulation. 

 

 

 

#2.  Protein Screening 


Screening for Protein-Protein Interaction 

 


 

# 3.  Drug Delivery 


Drug Delivery Systems

Administration of a drug is not limited to one method, there are different approaches, formulations, and delivery that all contribute to efficacy. Viscosity of the formulation can impact efficacy in many different ways. Learn more:   

 

 

 

# 4.  Hydrodynamic Radius

 

Characterization of Proteins

Hydrodynamic radius (Rh) is a common parameter used to describe a molecule's size. Understanding the characteristics of proteins can help understand protein behavior as proteins can be quite complex. 


 

 

# 5.  Whole Blood/ Blood Plasma/ Blood Serum 


Hemodynamics

Fluid dynamics in blood flow can help understand flow behavior when it comes to diagnostics and treatment of various conditions.

 

 


# 6.  Opthalmic Solutions 


Eye Drops

Eye drops or opthalmic solutions are a good example of where shear rates are a large contributing factor. 

 

 

 

# 7.   Protein Stability


Stable Protein is the Goal

Read our application notes where we touch base on protein stability and how to prolong stability. 

 



# 8.  RNA Therapeutics


RNA Therapies

RNA Therapies have been used for high-impact drug development. RNA Therapy plays in cellular activity and thus have been an advantage over small and large molecule compound therapies in certain ways.


     •  RNA Therapeutics Viscosity

 

 

 

# 9.   Antibody Therapeutics


Protein Therapeutics

Antibody therapeutics, an alternative method from RNA Therapeutics, is also equally viable when it comes to development combat methods against serious illnesses. See what factors will be important and what you should understand if you are in the industry.

 

  • •  Antibody Therapeutics - Monoclonal Antibodies 
  • •  Protein Therapeutics